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Assay Detail

CHEMBL834323

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against P-388 cell line (mouse T-cell leukemia cells)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type P388
Confidence 1 — Organism
Curated By Intermediate

Target

P388 (CHEMBL389)
Type CELL-LINE
Organism Mus musculus

Publication

Developing microcolin A analogs as biological probes.
Mandal AK, Hines J, Kuramochi K, Crews CM.
Bioorg Med Chem Lett (2005) 15 : 4043 -4047
PubMed 15993592 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.88 7.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL185931 1 7.18
CHEMBL428806 1 5.30
CHEMBL363234 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL185931 IC50 = 66.7 nM 7.18
CHEMBL428806 IC50 = 5000.0 nM 5.30
CHEMBL363234 IC50 = 7000.0 nM 5.16