Assay Detail

CHEMBL834398

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Cytotoxicity against Jurkat cell line (human T-cell leukemia cells)

ChEMBL ↗

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Target

Jurkat (CHEMBL397) ↗

Open DB target context

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Primary target Jurkat

CHEMBL397

Anchored from Assay target.

Protein identity Jurkat

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	Jurkat
Confidence	1 — Organism
Curated By	Intermediate

Target

Jurkat (CHEMBL397) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Developing microcolin A analogs as biological probes.

Mandal AK, Hines J, Kuramochi K, Crews CM.
Bioorg Med Chem Lett (2005) 15 : 4043 -4047
PubMed 15993592 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.41	7.41

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL185931	—	—	1	7.41

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL185931	—	IC50	=	39.4	nM	7.41