Assay Detail
Functional
CHEMBL834686
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Inhibitory concentration againstHuman cell lung carcinoma cell line NCI-H69; n=3
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H69 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.76 | 9.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL117142 | — | — | 1 | 9.06 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.95 |
| CHEMBL263256 | — | — | 1 | 7.87 |
| CHEMBL11359 | CISPLATIN | 4.0 | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL117142 | — | IC50 | = | 0.87 | nM | 9.06 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 11.3 | nM | 7.95 |
| CHEMBL263256 | — | IC50 | = | 13.4 | nM | 7.87 |
| CHEMBL11359 | CISPLATIN | IC50 | = | 683.0 | nM | 6.17 |