Assay Detail
Functional
CHEMBL840369
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Evaluated for its ability to inhibit electrically induced contractions in the mouse vas deferens (MVD)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Dermorphin sequence with high -afinity by fixing the phe sidechain to trans at 1
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.81 | 9.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL317956 | DELTORPHIN C | — | 1 | 9.49 |
| CHEMBL25465 | — | — | 1 | 9.18 |
| CHEMBL278789 | DERMORPHIN | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL317956 | DELTORPHIN C | IC50 | = | 0.32 | nM | 9.49 |
| CHEMBL25465 | — | IC50 | = | 0.66 | nM | 9.18 |
| CHEMBL278789 | DERMORPHIN | IC50 | = | 17.8 | nM | 7.75 |