Assay Detail
Functional
CHEMBL843343
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Evaluated for contractile activities of guinea pig ileum for agonistic activity
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Investigation of peripheral cholecystokinin receptor heterogeneity by cyclic and related linear analogues of CCK26-33: synthesis and biological properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 8.60 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1121 | SINCALIDE | 4.0 | 1 | 8.70 |
| CHEMBL384035 | — | — | 1 | 8.49 |
| CHEMBL216677 | — | — | 1 | - |
| CHEMBL439699 | — | — | 1 | - |
| CHEMBL2371662 | — | — | 1 | - |
| CHEMBL268849 | — | — | 1 | - |
| CHEMBL3037884 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1121 | SINCALIDE | EC50 | = | 2.0 | nM | 8.70 |
| CHEMBL384035 | — | EC50 | = | 3.2 | nM | 8.49 |
| CHEMBL216677 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL439699 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL2371662 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL268849 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL3037884 | — | EC50 | > | 10000.0 | nM | - |