Assay Detail
Functional
CHEMBL855307
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Cytotoxicity against human Jurkat cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Discovery of a novel series of inhibitors of human cytomegalovirus primase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.18 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL385536 | — | — | 1 | 4.60 |
| CHEMBL385412 | — | — | 1 | 4.10 |
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 4.00 |
| CHEMBL215727 | — | — | 1 | 4.00 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL385536 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL385412 | — | IC50 | = | 80000.0 | nM | 4.10 |
| CHEMBL5314375 | CIDOFOVIR | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL215727 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL182 | GANCICLOVIR | IC50 | > | 100000.0 | nM | - |