Assay Detail
Functional
CHEMBL856940
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against avian influenza virus H5N1 in MDCK cells measured as reduction in infected cells relative to control
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.37 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 5.55 |
| CHEMBL214997 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222813 | ZANAMIVIR | EC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL214997 | — | EC50 | = | 6400.0 | nM | 5.19 |