Assay Detail
Functional
CHEMBL857043
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for blocked alpha-methylhistamine-induced inhibition of electrical field-stimulation induced twitch response in guinea pig ileum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and SAR of aminoalkoxy-biaryl-4-carboxamides: novel and selective histamine H3 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 9.47 | 9.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27979 | A-349,821 | — | 1 | 9.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27979 | A-349,821 | Kd | = | 0.3388 | nM | 9.47 |