Assay Detail

CHEMBL857045

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Functional

Tested for inhibition of U-46619-induced contraction of the guinea pig lung membranes

ChEMBL ↗

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Target

Cavia porcellus (CHEMBL369) ↗

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Primary target Cavia porcellus

CHEMBL369

Anchored from Assay target.

Protein identity Cavia porcellus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Cavia porcellus
Tissue	Lung
Subcellular	Membrane
Confidence	1 — Organism
Curated By	Intermediate

Target

Cavia porcellus (CHEMBL369) ↗

Type	ORGANISM
Organism	Cavia porcellus

Publication

Antagonism of the TXA2 receptor by seratrodast: a structural approach.

Wouters J, Durant F, Masereel B.
Bioorg Med Chem Lett (1999) 9 : 2867 -2870
PubMed 10522708 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	8.29	8.29

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL70972	SERATRODAST	4.0	1	8.29

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL70972	SERATRODAST	Kd	=	5.129	nM	8.29