Assay Detail
Functional
CHEMBL858361
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Inhibition of methacholine induced tonic contraction of guinea pig ileum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, molecular modeling studies, and muscarinic receptor activity of azaprophen analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 9.06 | 10.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL320611 | — | — | 1 | 10.39 |
| CHEMBL110339 | — | — | 1 | 8.75 |
| CHEMBL322582 | — | — | 1 | 8.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL320611 | — | Kd | = | 0.04074 | nM | 10.39 |
| CHEMBL110339 | — | Kd | = | 1.778 | nM | 8.75 |
| CHEMBL322582 | — | Kd | = | 9.333 | nM | 8.03 |