Assay Detail
Binding
CHEMBL858413
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Compound was evaluated for its binding affinity on guinea-pig ileum
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
A new structural analogue antagonist of peptido-leukotrienes. The discovery of bay x7195
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.20 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL288943 | LEUKOTRIENE D4 | -1.0 | 1 | 9.00 |
| CHEMBL434013 | — | — | 1 | 8.70 |
| CHEMBL39876 | — | — | 1 | 8.70 |
| CHEMBL286626 | — | — | 1 | 7.60 |
| CHEMBL285954 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL288943 | LEUKOTRIENE D4 | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL434013 | — | Ki | = | 1.995 | nM | 8.70 |
| CHEMBL39876 | — | Ki | = | 1.995 | nM | 8.70 |
| CHEMBL286626 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL285954 | — | Ki | = | 100.0 | nM | 7.00 |