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Assay Detail

CHEMBL858827

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of Trypanosoma cruzi intracellular amastigotes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma cruzi
Confidence 1 — Organism
Curated By Expert

Target

Trypanosoma cruzi (CHEMBL368)
Type ORGANISM
Organism Trypanosoma cruzi

Publication

Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates.
Hudock MP, Sanz-Rodríguez CE, Song Y, Chan JM, Zhang Y, Odeh S, Kosztowski T, Leon-Rossell A, Concepción JL, Yardley V, Croft SL, Urbina JA, Oldfield E.
J Med Chem (2006) 49 : 215 -223
PubMed 16392806 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.00 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL200262 1 5.66
CHEMBL55371 1 4.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL200262 IC50 = 2200.0 nM 5.66
CHEMBL55371 IC50 = 47000.0 nM 4.33