Assay Detail
Functional
CHEMBL859544
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Cytotoxicity against human leukemic CEM cell line
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 6.05 | 7.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL202979 | — | — | 1 | 7.91 |
| CHEMBL382056 | — | — | 1 | 6.96 |
| CHEMBL383097 | — | — | 1 | 6.15 |
| CHEMBL201382 | — | — | 1 | 5.80 |
| CHEMBL380656 | — | — | 1 | 5.79 |
| CHEMBL201418 | — | — | 1 | 5.55 |
| CHEMBL201114 | — | — | 1 | 5.43 |
| CHEMBL197700 | — | — | 1 | 4.83 |
| CHEMBL378359 | — | — | 1 | - |
| CHEMBL202935 | — | — | 1 | - |
| CHEMBL421087 | — | — | 1 | - |
| CHEMBL382906 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL202979 | — | IC50 | = | 12.2 | nM | 7.91 |
| CHEMBL382056 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL383097 | — | IC50 | = | 715.0 | nM | 6.15 |
| CHEMBL201382 | — | IC50 | = | 1580.0 | nM | 5.80 |
| CHEMBL380656 | — | IC50 | = | 1640.0 | nM | 5.79 |
| CHEMBL201418 | — | IC50 | = | 2840.0 | nM | 5.55 |
| CHEMBL201114 | — | IC50 | = | 3710.0 | nM | 5.43 |
| CHEMBL197700 | — | IC50 | = | 14670.0 | nM | 4.83 |
| CHEMBL378359 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL202935 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL421087 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL382906 | — | IC50 | > | 25000.0 | nM | - |