Assay Detail
Binding
CHEMBL862182
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of VHR DS-PTP
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Dual specificity protein phosphatase 3 (CHEMBL2635) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Protein tyrosine phosphatase 1B inhibitors from Morus root bark.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.99 | 4.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL426373 | — | — | 1 | 4.99 |
| CHEMBL204813 | SANGGENON C | — | 1 | - |
| CHEMBL561971 | MORACIN P | — | 1 | - |
| CHEMBL205924 | MORACIN O | — | 1 | - |
| CHEMBL377937 | KUWANON L | — | 1 | - |
| CHEMBL378806 | MULBERROFURAN C | — | 1 | - |
| CHEMBL382338 | SANGGENON G | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL426373 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL204813 | SANGGENON C | IC50 | > | 80000.0 | nM | - |
| CHEMBL561971 | MORACIN P | IC50 | > | 80000.0 | nM | - |
| CHEMBL205924 | MORACIN O | IC50 | > | 80000.0 | nM | - |
| CHEMBL377937 | KUWANON L | IC50 | > | 80000.0 | nM | - |
| CHEMBL378806 | MULBERROFURAN C | IC50 | > | 80000.0 | nM | - |
| CHEMBL382338 | SANGGENON G | IC50 | > | 80000.0 | nM | - |