Assay Detail
ADMET
CHEMBL864246
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Inhibition of CYP2C9
5
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of N-substituted piperazine amine reuptake inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.64 | 4.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL534942 | — | — | 2 | 4.64 |
| CHEMBL540107 | — | — | 1 | - |
| CHEMBL534723 | — | — | 1 | - |
| CHEMBL213287 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL534942 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL534942 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL540107 | — | IC50 | - | — | - | |
| CHEMBL534723 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL213287 | — | IC50 | - | — | - |