Assay Detail
ADMET
CHEMBL864490
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Inhibitory activity against cytochrome P450 2C9 isoform
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.47 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2113208 | — | — | 1 | 6.48 |
| CHEMBL2113179 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2113208 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL2113179 | — | IC50 | = | 345.0 | nM | 6.46 |