Assay Detail
Binding
CHEMBL865879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against Protein phosphatase 1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (CHEMBL4438) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.67 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200117 | — | — | 1 | 6.66 |
| CHEMBL202197 | — | — | 1 | 5.89 |
| CHEMBL201662 | — | — | 1 | 4.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200117 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL202197 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL201662 | — | IC50 | = | 35200.0 | nM | 4.45 |