Assay Detail
Binding
CHEMBL869845
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CA5a
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Carbonic anhydrase 5A, mitochondrial (CHEMBL4789) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.28 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL213348 | — | — | 1 | 6.04 |
| CHEMBL467 | HYDROXYUREA | 4.0 | 1 | 4.51 |
| CHEMBL734 | ACETOHYDROXAMIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL213348 | — | Ki | = | 910.0 | nM | 6.04 |
| CHEMBL467 | HYDROXYUREA | Ki | = | 31000.0 | nM | 4.51 |
| CHEMBL734 | ACETOHYDROXAMIC ACID | Ki | - | — | - |