Assay Detail
Binding
CHEMBL870570
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DAMGO from mu opioid receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of the first cyclic biphalin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.32 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200129 | — | — | 1 | 9.22 |
| CHEMBL200199 | BIPHALIN | — | 1 | 8.85 |
| CHEMBL372787 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200129 | — | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL200199 | BIPHALIN | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL372787 | — | IC50 | = | 130.0 | nM | 6.89 |