Assay Detail
Binding
CHEMBL871423
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Displacement of [125I]DOI from rat 5HT2A receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.98 | 8.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL263881 | LYSERGIDE | 2.0 | 1 | 8.46 |
| CHEMBL379780 | — | — | 1 | 7.16 |
| CHEMBL211309 | — | — | 1 | 6.89 |
| CHEMBL26687 | MESCALINE | 1.0 | 1 | 6.44 |
| CHEMBL211301 | — | — | 1 | 5.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL263881 | LYSERGIDE | Ki | = | 3.5 | nM | 8.46 |
| CHEMBL379780 | — | Ki | = | 69.0 | nM | 7.16 |
| CHEMBL211309 | — | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL26687 | MESCALINE | Ki | = | 360.0 | nM | 6.44 |
| CHEMBL211301 | — | Ki | = | 1120.0 | nM | 5.95 |