Assay Detail
Functional
CHEMBL871937
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Bioactivity in vitro in guinea pig ileum (GPI) isolated organ preparation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.58 | 8.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278789 | DERMORPHIN | — | 1 | 8.68 |
| CHEMBL1790778 | — | — | 1 | 8.51 |
| CHEMBL2369626 | — | — | 1 | 7.66 |
| CHEMBL2370329 | — | — | 1 | 5.47 |
| CHEMBL2370333 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278789 | DERMORPHIN | IC50 | = | 2.1 | nM | 8.68 |
| CHEMBL1790778 | — | IC50 | = | 3.1 | nM | 8.51 |
| CHEMBL2369626 | — | IC50 | = | 22.1 | nM | 7.66 |
| CHEMBL2370329 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL2370333 | — | IC50 | > | 4000.0 | nM | - |