Assay Detail
Binding
CHEMBL872660
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro binding affinity against bovine striatal membrane using [3H]pirenzepine
10
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Tissue | Striatum |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 9.09 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL297276 | — | — | 2 | 9.96 |
| CHEMBL296895 | — | — | 1 | 9.70 |
| CHEMBL12980 | QUINUCLIDINYL BENZILATE | — | 1 | 9.66 |
| CHEMBL296633 | — | — | 1 | 9.59 |
| CHEMBL298085 | — | — | 1 | 9.47 |
| CHEMBL49576 | — | — | 1 | 9.08 |
| CHEMBL47650 | — | — | 2 | 9.05 |
| CHEMBL297683 | — | — | 1 | 8.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL297276 | — | Ki | = | 0.11 | nM | 9.96 |
| CHEMBL296895 | — | Ki | = | 0.2 | nM | 9.70 |
| CHEMBL12980 | QUINUCLIDINYL BENZILATE | Ki | = | 0.22 | nM | 9.66 |
| CHEMBL296633 | — | Ki | = | 0.26 | nM | 9.59 |
| CHEMBL298085 | — | Ki | = | 0.34 | nM | 9.47 |
| CHEMBL49576 | — | Ki | = | 0.84 | nM | 9.08 |
| CHEMBL47650 | — | Ki | = | 0.89 | nM | 9.05 |
| CHEMBL297683 | — | Ki | = | 4.6 | nM | 8.34 |
| CHEMBL47650 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL297276 | — | Ki | = | 17.9 | nM | 7.75 |