Assay Detail
Functional
CHEMBL872815
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against P388 murine leukemia cell which is topoisomerase II enzyme and resistant to classical topo II Inhibitors
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Potential antitumor agents. 64. Synthesis and antitumor evaluation of dibenzo[1,4]dioxin-1-carboxamides: a new class of weakly binding DNA-intercalating agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.06 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL88777 | — | — | 1 | 6.08 |
| CHEMBL88802 | — | — | 1 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL88777 | — | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL88802 | — | IC50 | = | 930.0 | nM | 6.03 |