Assay Detail
Binding
CHEMBL873055
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Inhibition of human placental adenosine kinase
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New adenosine kinase inhibitors with oral antiinflammatory activity: synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.70 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99203 | IODOTUBERCIDIN | — | 1 | 7.52 |
| CHEMBL608051 | — | — | 1 | 7.40 |
| CHEMBL607761 | — | — | 1 | 6.82 |
| CHEMBL607766 | — | — | 1 | 6.80 |
| CHEMBL612205 | — | — | 1 | 6.77 |
| CHEMBL611890 | — | — | 1 | 6.52 |
| CHEMBL607762 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99203 | IODOTUBERCIDIN | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL608051 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL607761 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL607766 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL612205 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL611890 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL607762 | — | Ki | = | 8500.0 | nM | 5.07 |