Compound Detail
CHEMBL607766
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL607766 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IMJPAOAGQBDOMO-RMXRYUSWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
395.1
MW (Da)
-0.40
ALogP
8
HBA
3
HBD
119.3
PSA (Ų)
0.59
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Adenosine kinase CHEMBL3589 | Ki | 6.8 | 6.8 | 160.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Adenosine kinase | Ki | = | 160.0 | nM | 6.8 | Inhibition of human placental adenosine kinase | 8230132 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8230132 | 10.1021/jm00074a024 | Adenosine kinase | 3 |
| 8230132 | 10.1021/jm00074a024 | CCRF-CEM | 1 |
Data from ChEMBL 36 via Core Engine