Assay Detail

CHEMBL873619

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Functional

Cytotoxic activity against P-388 mouse leukemia cell lines.

ChEMBL ↗

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Target

P388 (CHEMBL389) ↗

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Primary target P388

CHEMBL389

Anchored from Assay target.

Protein identity P388

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Cell Type	P388
Confidence	1 — Organism
Curated By	Intermediate

Target

P388 (CHEMBL389) ↗

Type	CELL-LINE
Organism	Mus musculus

Publication

The enediyne antibiotics.

Smith AL, Nicolaou KC.
J Med Chem (1996) 39 : 2103 -2117
PubMed 8667354 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.34	8.34

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL302778	—	—	1	8.34

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL302778	—	IC50	=	4.6	nM	8.34