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Assay Detail

CHEMBL873920

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]diprenorphine (0.33 nM) binding from human Opioid receptor mu 1 expressed in CHO-K1 cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO-K1
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mu-type opioid receptor (CHEMBL233)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
Shinkai H, Ito T, Iida T, Kitao Y, Yamada H, Uchida I.
J Med Chem (2000) 43 : 4667 -4677
PubMed 11101358 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.99 6.99

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL140979 1 6.99

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL140979 Ki = 102.9 nM 6.99