Assay Detail
Functional
CHEMBL877910
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of production of beta-galactosidase IL-2 RGA in Jurkat cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.72 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL160 | CYCLOSPORINE | 4.0 | 1 | 8.10 |
| CHEMBL16870 | — | — | 1 | 5.33 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | — | 1 | - |
| CHEMBL314035 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL160 | CYCLOSPORINE | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL16870 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | IC50 | > | 22000.0 | nM | - |
| CHEMBL314035 | — | IC50 | > | 100000.0 | nM | - |