Assay Detail
Functional
CHEMBL878951
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Dissociation constant of the drug-receptor complex was measured in guinea pig ileum
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Dimethylsulfonium and thiolanium analogues of the muscarinic agent oxotremorine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 5.51 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL553214 | — | — | 1 | 5.89 |
| CHEMBL540395 | — | — | 1 | 5.82 |
| CHEMBL23957 | OXOTREMORINE METHIODIDE | — | 1 | 5.54 |
| CHEMBL541927 | — | — | 1 | 5.16 |
| CHEMBL554629 | — | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL553214 | — | Kd | = | 1300.0 | nM | 5.89 |
| CHEMBL540395 | — | Kd | = | 1500.0 | nM | 5.82 |
| CHEMBL23957 | OXOTREMORINE METHIODIDE | Kd | = | 2900.0 | nM | 5.54 |
| CHEMBL541927 | — | Kd | = | 6900.0 | nM | 5.16 |
| CHEMBL554629 | — | Kd | = | 7500.0 | nM | 5.12 |