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Assay Detail

CHEMBL879037

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of the Schulz-Dale (SD) reaction-induced contraction in trachea of guinea pig
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Trachea
Confidence 1 — Organism
Curated By Intermediate

Target

Cavia porcellus (CHEMBL369)
Type ORGANISM
Organism Cavia porcellus

Publication

New bronchodilators. 1. 1,5-Substituted 1H-imidazo[4,5-c]quinolin-4(5H)-ones.
Suzuki F, Kuroda T, Nakasato Y, Manabe H, Ohmori K, Kitamura S, Ichikawa S, Ohno T.
J Med Chem (1992) 35 : 4045 -4053
PubMed 1331454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL434802 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL434802 IC50 = 250.0 nM 6.60