Assay Detail
Functional
CHEMBL879363
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Inhibition of forskolin stimulated cAMP production in neonatal rat pituitary
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of a novel series of tricyclic indan derivatives as melatonin receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.39 | 10.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1218 | RAMELTEON | 4.0 | 1 | 10.68 |
| CHEMBL45 | MELATONIN | 4.0 | 1 | 10.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1218 | RAMELTEON | IC50 | = | 0.0208 | nM | 10.68 |
| CHEMBL45 | MELATONIN | IC50 | = | 0.0798 | nM | 10.10 |