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Assay Detail

CHEMBL879866

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Binding
Compound was evaluated for the binding affinity against dopamine (D1) receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL339)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis and molecular modeling of 1-phenyl-1,2,3,4-tetrahydroisoquinolines and related 5,6,8,9-tetrahydro-13bH-dibenzo[a,h]quinolizines as D1 dopamine antagonists.
Minor DL, Wyrick SD, Charifson PS, Watts VJ, Nichols DE, Mailman RB.
J Med Chem (1994) 37 : 4317 -4328
PubMed 7996543 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.73 5.73

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL303993 1 5.73

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL303993 Ki = 1862.09 nM 5.73