Assay Detail
Binding
CHEMBL881470
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards rat dopamine D2 receptor using [11C] radiotracer
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
11C-labeling of n-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]arylcarboxamide derivatives and evaluation as potential radioligands for PET imaging of dopamine D3 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.14 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL345820 | — | — | 1 | 6.14 |
| CHEMBL196476 | — | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL345820 | — | Ki | = | 720.0 | nM | 6.14 |
| CHEMBL196476 | — | Ki | = | 720.0 | nM | 6.14 |