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Assay Detail

CHEMBL884338

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibitory effect on human recombinant liver cytochrome P450 2C9 expressed in yeast strain
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Cytochrome P450 2C9 (CHEMBL3397)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily.
Ha-Duong NT, Dijols S, Marques-Soares C, Minoletti C, Dansette PM, Mansuy D.
J Med Chem (2001) 44 : 3622 -3631
PubMed 11606127 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.92 4.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL333108 1 4.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL333108 IC50 = 12000.0 nM 4.92