Assay Detail
Functional
CHEMBL884344
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro extracellular concentration required to reduce cell population to 50% against Chinese hamster V79 cells
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | V79 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anthracene-9,10-diones as potential anticancer agents. Synthesis, DNA-binding, and biological studies on a series of 2,6-disubstituted derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.21 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33505 | — | — | 1 | 5.80 |
| CHEMBL33618 | — | — | 1 | 5.77 |
| CHEMBL33564 | — | — | 1 | 5.75 |
| CHEMBL34683 | — | — | 1 | 5.54 |
| CHEMBL33801 | — | — | 1 | 5.44 |
| CHEMBL263805 | — | — | 1 | 5.40 |
| CHEMBL446136 | — | — | 1 | 5.34 |
| CHEMBL34401 | — | — | 1 | 4.92 |
| CHEMBL33674 | — | — | 1 | 4.75 |
| CHEMBL34388 | — | — | 1 | 4.71 |
| CHEMBL33760 | — | — | 1 | 4.59 |
| CHEMBL34393 | — | — | 1 | 4.52 |
| CHEMBL33585 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33505 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL33618 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL33564 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL34683 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL33801 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL263805 | — | IC50 | = | 3950.0 | nM | 5.40 |
| CHEMBL446136 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL34401 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL33674 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL34388 | — | IC50 | = | 19500.0 | nM | 4.71 |
| CHEMBL33760 | — | IC50 | = | 25500.0 | nM | 4.59 |
| CHEMBL34393 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL33585 | — | IC50 | > | 100000.0 | nM | - |