Compound Detail
CHEMBL34393
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Basic Information
| ChEMBL ID | CHEMBL34393 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UNLMJDNVVZDULE-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
488.6
MW (Da)
3.31
ALogP
6
HBA
2
HBD
98.8
PSA (Ų)
0.55
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.52 | 4.52 | 30000.0 | 1 |
| L1210 CHEMBL386 | IC50 | 4.12 | 4.12 | 76000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 30000.0 | nM | 4.52 | In vitro extracellular concentration required to reduce cell population to 50% a... | 1573635 |
| L1210 | IC50 | = | 76000.0 | nM | 4.12 | In vitro extracellular concentration required to reduce cell population to 50% a... | 1573635 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1573635 | 10.1021/jm00086a010 | Nucleic Acid | 5 |
| 1573635 | 10.1021/jm00086a010 | NON-PROTEIN TARGET | 2 |
| 1573635 | 10.1021/jm00086a010 | L1210 | 1 |
| 1573635 | 10.1021/jm00086a010 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine