Assay Detail
Binding
CHEMBL885059
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required for 50% inhibition of Cholecystokinin type A receptor in rat pancreatic tissue
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Cholecystokinin receptor type A (CHEMBL2871) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
2002 Alfred Burger Award Address in Medicinal Chemistry. Natural products and design: interrelated approaches in drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.50 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL9506 | DEVAZEPIDE | 2.0 | 1 | 10.10 |
| CHEMBL9387 | L-365260 | — | 1 | 6.55 |
| CHEMBL357749 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL9506 | DEVAZEPIDE | IC50 | = | 0.08 | nM | 10.10 |
| CHEMBL9387 | L-365260 | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL357749 | — | IC50 | = | 1400.0 | nM | 5.85 |