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Assay Detail

CHEMBL893298

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine kidney alpha-L-fucosidase
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and evaluation of amino-threoses in D- and L-series: are five membered ring amino-sugars more potent glycosidase inhibitors than the six membered ones?
Chevrier C, Defoin A, Tarnus C.
Bioorg Med Chem (2007) 15 : 4125 -4135
PubMed 17434740 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 5.52 5.52
IC50 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL389969 1 5.52
CHEMBL389595 1 -
CHEMBL396701 1 -
CHEMBL396702 1 -
CHEMBL232244 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL389969 Ki = 3000.0 nM 5.52
CHEMBL389595 Ki - -
CHEMBL396701 Ki - -
CHEMBL396702 Ki - -
CHEMBL232244 IC50 = 1000000.0 nM -