Compound Detail
CHEMBL389595
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL389595 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FNRDSSFSPPAIRA-UZBSEBFBSA-N |
2
Targets
4
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
119.1
MW (Da)
-2.37
ALogP
4
HBA
4
HBD
72.7
PSA (Ų)
0.29
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas.
Ki 2 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glucoamylase, intracellular sporulation-specific CHEMBL1075248 | Ki | 5.7 | 5.7 | 2000.0 | 1 |
| Unchecked CHEMBL612545 | Ki | 5.3 | 5.3 | 5000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glucoamylase, intracellular sporulation-specific | Ki | = | 2000.0 | nM | 5.7 | Inhibition of yeast alpha-D-glucosidase | 17434740 |
| Unchecked | Ki | = | 5000.0 | nM | 5.3 | Inhibition of jack bean alpha-D-mannosidase | 17434740 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17434740 | 10.1016/j.bmc.2007.03.073 | Unchecked | 7 |
| 17434740 | 10.1016/j.bmc.2007.03.073 | Glucoamylase, intracellular sporulation-specific | 1 |
Data from ChEMBL 36 via Core Engine