Assay Detail
Binding
CHEMBL893291
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of jack bean alpha-D-mannosidase
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Canavalia ensiformis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of amino-threoses in D- and L-series: are five membered ring amino-sugars more potent glycosidase inhibitors than the six membered ones?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.25 | 5.70 |
| IC50 | 2 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL232244 | — | — | 1 | 5.70 |
| CHEMBL389294 | NECTRISINE | — | 1 | 5.52 |
| CHEMBL395524 | — | — | 1 | 5.30 |
| CHEMBL389595 | — | — | 1 | 5.30 |
| CHEMBL389969 | — | — | 1 | 4.70 |
| CHEMBL120638 | NOJIRIMYCIN | — | 1 | - |
| CHEMBL396702 | — | — | 1 | - |
| CHEMBL80254 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL232244 | — | Ki | = | 2000.0 | nM | 5.70 |
| CHEMBL389294 | NECTRISINE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL395524 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL389595 | — | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL389969 | — | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL120638 | NOJIRIMYCIN | Ki | = | 500000.0 | nM | - |
| CHEMBL396702 | — | Ki | - | — | - | |
| CHEMBL80254 | — | IC50 | = | 200000.0 | nM | - |