Compound Detail
CHEMBL120638
NOJIRIMYCIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL120638 |
| Name | NOJIRIMYCIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BGMYHTUCJVZIRP-GASJEMHNSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
179.2
MW (Da)
-3.65
ALogP
6
HBA
6
HBD
113.2
PSA (Ų)
0.25
QED
1
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 6.05 | 6.05 | 900.0 | 1 |
| Glucoamylase, intracellular sporulation-specific CHEMBL1075248 | Ki | 5.2 | 5.2 | 6300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 900.0 | nM | 6.05 | Inhibition of almond beta-D-glucosidase | 17434740 |
| Glucoamylase, intracellular sporulation-specific | Ki | = | 6300.0 | nM | 5.2 | Inhibition of yeast alpha-D-glucosidase | 17434740 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17434740 | 10.1016/j.bmc.2007.03.073 | Unchecked | 3 |
| - | 10.1016/S0960-894X(97)00012-7 | Sucrase-isomaltase, intestinal | 2 |
| - | 10.1016/S0960-894X(97)00012-7 | Maltase-glucoamylase | 1 |
| 17434740 | 10.1016/j.bmc.2007.03.073 | Glucoamylase, intracellular sporulation-specific | 1 |
Data from ChEMBL 36 via Core Engine