Assay Detail
Binding
CHEMBL893290
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of almond beta-D-glucosidase
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Prunus dulcis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of amino-threoses in D- and L-series: are five membered ring amino-sugars more potent glycosidase inhibitors than the six membered ones?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.66 | 5.66 |
| Ki | 3 | 6.29 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL232244 | — | — | 1 | 6.52 |
| CHEMBL120638 | NOJIRIMYCIN | — | 1 | 6.05 |
| CHEMBL389294 | NECTRISINE | — | 1 | 5.66 |
| CHEMBL395524 | — | — | 1 | - |
| CHEMBL389595 | — | — | 1 | - |
| CHEMBL232457 | — | — | 1 | - |
| CHEMBL396702 | — | — | 1 | - |
| CHEMBL80254 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL232244 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL120638 | NOJIRIMYCIN | Ki | = | 900.0 | nM | 6.05 |
| CHEMBL389294 | NECTRISINE | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL395524 | — | IC50 | = | 180000.0 | nM | - |
| CHEMBL389595 | — | IC50 | = | 200000.0 | nM | - |
| CHEMBL232457 | — | IC50 | = | 2000000.0 | nM | - |
| CHEMBL396702 | — | Ki | - | — | - | |
| CHEMBL80254 | — | IC50 | = | 500000.0 | nM | - |