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Compound Detail

CHEMBL232244

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O[C@@H]1C=NC[C@@H]1O

Basic Information

ChEMBL ID CHEMBL232244
Phase Preclinical
Structure Type MOL
InChI Key RTVUDPFAUMGQAC-DMTCNVIQSA-N
1
Targets
5
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

101.1
MW (Da)
-1.21
ALogP
3
HBA
2
HBD
52.8
PSA (Ų)
0.40
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C4H7NO2
MW 101.10
Aromatic Rings 0
Heavy Atoms 7
NP-Likeness 1.38

Activity Summary

Ki 4 meas. best 6.7
IC50 1 meas.

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 6.7 6.405 200.0 4

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
17434740 10.1016/j.bmc.2007.03.073 Unchecked 5

Data from ChEMBL 36 via Core Engine