Assay Detail
Functional
CHEMBL897879
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Antiparasitic activity against Trypanosoma cruzi Y amastigotes infected gamma irradiated L6E9 myoblast
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Fluorine-containing aryloxyethyl thiocyanate derivatives are potent inhibitors of Trypanosoma cruzi and Toxoplasma gondii proliferation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.06 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL397366 | — | — | 1 | 5.43 |
| CHEMBL236089 | — | — | 1 | 5.37 |
| CHEMBL39581 | — | — | 1 | 4.92 |
| CHEMBL235669 | — | — | 1 | 4.84 |
| CHEMBL238006 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL397366 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL236089 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL39581 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL235669 | — | IC50 | = | 14400.0 | nM | 4.84 |
| CHEMBL238006 | — | IC50 | = | 19000.0 | nM | 4.72 |