Assay Detail
Toxicity
CHEMBL903468
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Neurotoxicity against mouse P19 derived neurons after 18 hrs
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Geldanamycin derivatives and neuroprotective effect on cultured P19-derived neurons.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.57 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL397319 | — | — | 1 | 5.80 |
| CHEMBL278315 | GELDANAMYCIN | 2.0 | 1 | 5.75 |
| CHEMBL391544 | — | — | 1 | 5.17 |
| CHEMBL391545 | — | — | 1 | - |
| CHEMBL443488 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL397319 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL278315 | GELDANAMYCIN | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL391544 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL391545 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL443488 | — | IC50 | > | 10000.0 | nM | - |