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Assay Detail

CHEMBL905427

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Functional
Antioxidant activity assessed as superoxide radical anion scavenging activity
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus.
Lee IK, Yun BS.
Bioorg Med Chem (2007) 15 : 3309 -3314
PubMed 17387019 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.59 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL226019 INTERFUNGIN B 1 5.75
CHEMBL145 CAFFEIC ACID 3.0 1 5.66
CHEMBL388592 INTERFUNGIN A 1 5.57
CHEMBL226020 INTERFUNGIN C 1 5.51
CHEMBL3989727 VITAMIN E 4.0 1 5.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL226019 INTERFUNGIN B IC50 = 1800.0 nM 5.75
CHEMBL145 CAFFEIC ACID IC50 = 2200.0 nM 5.66
CHEMBL388592 INTERFUNGIN A IC50 = 2700.0 nM 5.57
CHEMBL226020 INTERFUNGIN C IC50 = 3100.0 nM 5.51
CHEMBL3989727 VITAMIN E IC50 = 3400.0 nM 5.47