Assay Detail
Functional
CHEMBL907249
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as cAMP levels
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Potent benzimidazolone based human beta(3)-adrenergic receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 8.62 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL218210 | — | — | 1 | 8.62 |
| CHEMBL386016 | — | — | 1 | - |
| CHEMBL374867 | — | — | 1 | - |
| CHEMBL221188 | — | — | 1 | - |
| CHEMBL434763 | — | — | 1 | - |
| CHEMBL384560 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL218210 | — | EC50 | = | 2.4 | nM | 8.62 |
| CHEMBL386016 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL374867 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL221188 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL434763 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL384560 | — | EC50 | > | 10000.0 | nM | - |