Assay Detail
Binding
CHEMBL910308
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of non-phosphorylated form of rabbit muscle glycogen phosphorylase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Tissue | Muscle tissue |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Glycogen phosphorylase, muscle form (CHEMBL4696) ↗| Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
Publication
Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.14 | 6.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL215137 | — | — | 1 | 6.41 |
| CHEMBL213661 | — | — | 1 | 6.08 |
| CHEMBL206468 | AFEGOSTAT | 2.0 | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL215137 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL213661 | — | IC50 | = | 840.0 | nM | 6.08 |
| CHEMBL206468 | AFEGOSTAT | IC50 | = | 1210.0 | nM | 5.92 |