Assay Detail
ADMET
CHEMBL911063
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Cytotoxicity against DU145 cells after 72 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.20 | 4.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL483849 | — | — | 1 | 4.23 |
| CHEMBL109480 | TANESPIMYCIN | 3.0 | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL483849 | — | IC50 | = | 59000.0 | nM | 4.23 |
| CHEMBL109480 | TANESPIMYCIN | IC50 | = | 68300.0 | nM | 4.17 |