Assay Detail
Binding
CHEMBL911097
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Activity at delta opioid receptor in ICR mouse by MVD assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.80 | 8.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200199 | BIPHALIN | — | 1 | 8.57 |
| CHEMBL386212 | — | — | 1 | 7.92 |
| CHEMBL375359 | — | — | 1 | 7.82 |
| CHEMBL217957 | — | — | 1 | 7.80 |
| CHEMBL218600 | — | — | 1 | 7.75 |
| CHEMBL414087 | — | — | 1 | 7.62 |
| CHEMBL218651 | — | — | 1 | 7.60 |
| CHEMBL407198 | — | — | 1 | 7.58 |
| CHEMBL386186 | — | — | 1 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200199 | BIPHALIN | IC50 | = | 2.7 | nM | 8.57 |
| CHEMBL386212 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL375359 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL217957 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL218600 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL414087 | — | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL218651 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL407198 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL386186 | — | IC50 | = | 31.0 | nM | 7.51 |